重组人CD45蛋白（His标记）
货号：106459 编号：XFBM469
CAS号： 规格：CD45, PTPRC, L-CA, T200
包装：10 μg 保质期：365天
保存条件：-20℃保存
.png)
.png)
{{language.person.wx}}
.png)
{{language.person.phone}}
.png)
{{language.person.message}}
DESCRIPTION | |
Gene Name Synonym | CD45, PTPRC, L-CA, T200 |
Species | Human |
Accession | P08575 |
Source | HEK293 cells |
SPECIFICATIONS | |
Amino acid sequence | Gln26-Asn575 is expressed with a 10×His tag at the C terminus |
Molecular Weight | 60.6 kDa |
Purity | >95.0% as determined by SDS-PAGE |
Endotoxin | <5 EU mg-1 |
Formulation | Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. |
Reconstitution | Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. |
STORAGE | |
Stability and Storage | 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. |
BACKGROUND | |
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes. CD45, the first and prototypic receptor-like protein tyrosine phosphatase, is expressed on all nucleated hematopoietic cells. CD45, is one of the key players in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency results in T-and B-lymphocyte dysfunction in the form of severe combined immune deficiency. Expression of CD45 is essential for the activation of T cells via the TCR, and that different CD45 isoforms display a different ability to support T cell activation. | |
Data | |
SDS-PAGE | Bioactivity |
| Testing in progress. |
Recombinant Human CD45 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 120-140 kDa. | |
快递服务
江浙沪皖用户邮费为10元，其他地区用户邮费为20， 国际运费请咨询sales@xfnano.com。购买满 500.0 元免运费。如果库存显示为0， 请电话或邮件和销售确认，免费热线电话：400 025 3200邮件：sale@xfnano.com 感谢您的支持！
推荐商品
